Twelve (86%) children were under two years of age. Since none of these authors reported the total number of patients in each age group, the increased incidence of labial fusion in these studies may have been related to the number of patients seen in each age group. Leung et al examined 1970 female children between seven days and 12 years of age to determine the incidence of labial fusion. Thirty-five (1.8%) of the children had labial fusion. The fusion was noted in only the first four years of life. The peak incidence occurred in the second year of life. The age distribution of the patients with and without labial fusion is shown in Table 1.
ETIOLOGY AND PATHOGENESIS
Labial fusion is considered to be an acquired condition that probably develops after denudation of the superficial squamous epithelial layer of the labial mucosa. During the healing process, fibrous tissue forms and agglutination develops in the opposed areas. Typically, the process begins posteriorly, and may ultimately cover the vaginal vestibule. You will always be glad to know there is a perfect pharmacy waiting for you whenever you need buy cheap asthma inhalers and would like to make sure you are taken best care of as a customer and patient.
Labial fusion occasionally persists to puberty and has, very rarely, been reported in postmenopausal women.
Denudation of the labial epithelium develops with inflammatory conditions of the labia minora such as vulvitis or vulvovaginitis. Pierce and Hart reported labial fusion in 14 of 200 (7%) girls with vulvovaginitis. In children, most cases of vulvitis or vulvovaginitis are due to chemical or infectious inflammation. Inflammation is often secondary to poor perineal hygiene and may be associated with asymptomatic bacteriuria or urinary tract infection . Inflammation may also develop consequent to seborrhea or atopic dermatitis. In children, pinworms may cause vulvovaginitis.