Left atrial appendage thrombus: Risk factor or source of cerebral embolism in patients with nonvalvular atrial fibrillation? (part 1)

Atrial fibrillation

Atrial fibrillation is a widely known risk factor for ischemic stroke. It is assumed that the pathomechanism of stroke in patients with atrial fibrillation is in most cases related to the formation and fragmentation of left atrial thrombus. Observations seem to confirm this hypothesis indirectly, such as the high incidence of atrial thrombi at autopsy and in the left atrial appendage at transesophageal echocardiography (TEE) in patients with atrial fibrillation and stroke , and high early recurrence of cerebral embolism in stroke patients with atrial fibrillation . You now have a chance to make sure your disease is under complete control. Being able to buy your drugs from means you will be spending less time and money every time, getting the same high quality.

TEE results (monoplane probe, HP Sonos 1000, Hewlett Packard, Palo Alto, California, USA) were retrospectively compared from patients with nonvalvular atrial fibrillation who were not on anticoagulation treatment before and at the time of examination. They were selected from about 800 patients studied by TEE at the authors’ laboratory between 1991 and 1995. Patients were divided into three groups: group C – the control group – comprised 158 patients with atrial fibrillation of more than three days’ duration, with no history of stroke; group O – ‘old’ ischemic stroke – comprised 17 patients with atrial fibrillation lasting more than three days and a history of ischemic stroke that occurred more than three months before TEE; and group R – recent ischemic stroke – comprised 22 patients with atrial fibrillation at the time of TEE and with recent (less than seven days) ischemic stroke.

This entry was posted in Cardiology and tagged Atrial fibrillation, Left atrial appendage thrombus, Spontaneous echocardiographic contrast, Stroke.