Prevalence and Correlates of Respiratory Symptoms and Disease in the Elderly: Eligibility

The following were exclusion factors: institutionalization, terminal illness, inability to walk, communicate, or give informed consent, or likely to move from the area the next 3 years. Potential participants were sent an explanatory letter, interviewed by telephone to determine eligibility, and then scheduled for the baseline clinic examination at the field center. Among those contacted and eligible, 57.6 percent were enrolled. Enrolled CHS participants were younger, more educated, and more likely to be married than those who refused or were ineligible. The CHS design and recruitment are described in detail elsewhere. The research protocol was reviewed and approved by the institutional review board for human studies of each clinical center and a complete informed consent was obtained from all participants.
Baseline examinations took place during the 12 months starting June 1989. Along with multiple other questionnaires, a subset of the standardized American Thoracic Society ATS DLD-78 Respiratory Questionnaire was administered by a centrally trained interviewer More info canadianfamilypharmacy. The exact wording and sequence of the ATS questions was maintained. Participants were asked to fast for 12 hours before the morning interview and examination. Examination components included spirometry, random-zero seated blood pressure, resting 12-lead ECG, echocardiography, carotid ultrasound, blood chemistry and lipid analysis, and a physical examination, detailed previously.
Eight spirometry technicians were centrally trained and certified prior to recruitment of participants. Training included a 16-hour National Institute for Occupational Safety and Health-approved spirometry course, using the CHS Manual of Procedures as a textbook, as well as a course in standardized interviewing techniques. The quality of spirometry tests done by the technicians was then monitored centrally and reported monthly throughout the 12 months of baseline testing.

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