Pulmonary Function Before Surgery for Pectus Excavatum and at Long-term Follow-up: Statistics

Pulmonary Function Before Surgery for Pectus Excavatum and at Long-term Follow-up: StatisticsThe preoperative ratio between the measured IVC/predicted IVC was not related to pulmonary complaints (p=0.336). On the other hand, we did find a significant relation between the presence of one or more pulmonary complaints (decreased exercise tolerance, easy fatiguability, inability to take deep breaths, and shortness of breath on exertion) and obstructive disease as expressed by the ratio FEVi/IVC as a percentage of predicted (p=0.042). Symptoms of retrosternal pain and palpitations were not related to preoperative lung function. The severity of the deformity did not influence the various lung functions.
The preoperative TLC, IVC, and FEVi as a percentage of predicted were significantly related to the SLVI (p=0.0001); however, relation coefficients were low: —0.452, —0.451, and —0.388, respectively. A significant relation was found between the SLVI and the severity of the deformity at physical examination (p=0.0107); however, there was no significant relation between the severity of the deformity and the results of the various lung function tests. No correlation was found between the SLVI and the preoperative FRC as a percentage of predicted, RV as a percentage of predicted, and the ratio FEVi/IVC as a percentage of predicted.
Graded according to Humphreys and Jaretzki, satisfactory results at long-term follow-up were observed in 83.6 percent (excellent, 44.1 percent; good, 39.5 percent). In 25 patients (16.4 percent), the results were unsatisfactory (fair, 10.5 percent; poor, 5.9 percent) mycanadianpharmacy.com.
We found no correlation between the changes in the results of the pulmonary lung function tests measured at follow-up and the surgical results. The changes in the results of the pulmonary function tests at follow-up were correlated with the age at surgery, follow-up interval, preoperative 5LVI, and the postoperative change in 6LVI (Spearman correlation coefficient). Only the age at surgery and the change in the TLC and IVC at follow-up were significantly related (p=0.0036 and 0.0043, respectively), however, the correlation coefficients were low (r=27 percent and 28 percent, respectively). Other authors reported that postoperative reduction in lung function was most pronounced in the patients who had the least functional impairment preoperatively (>75 percent predicted). An evaluation of our data using the Wilcoxon test showed that if the preoperative TLC was more than 75 percent of predicted, the change in the TLC at follow-up was more pronounced (—12.2±10.3 vs —7.4±8.2; p=0.0163); similarly if the preoperative IVC was more than 75 percent of predicted, its reduction at follow-up was more pronounced (—9.0±9.7 vs —6.2 ±10.6), although not significant.

This entry was posted in Pulmonary Function and tagged anteroposterior, cardiorespiratory, lung volumes, pulmonary function.