Tag Archives: anterior inferior

Effect of Infarct Site on Diastolic Time During Exercise: Limitations

There is a greater degree of shortening of the anterior than of the posterior wall during systole in the normal left ventricle, indicating that a similar degree of myocardial damage results in more impairment of left ventricular function after anterior MI. Furthermore, Wynne et al reported that abnormal regional ejection fraction in the segments remote from infarct zone was more frequent after anterior than in … Continue reading

Effect of Infarct Site on Diastolic Time During Exercise: Discussion

Clinical Findings The extent of myocardial necrosis is of primary importance in determining left ventricular function. Peak creatine kinase is reported to correlate with total creatine kinase and with infarct size at autopsy, but this method has certain limitations. After inferior MI, peak level of creatine kinase may not accurately reflect the extent of necrosis of the left ventricle because the right ventricle may have … Continue reading

Effect of Infarct Site on Diastolic Time During Exercise: Results

In all 21 patients, the bicycle exercise was terminated by exercising muscle fatigue without chest pain or ischemic electrocardiographic response. Exercise duration was 9±3 min in patients with anterior MI and 9 ± 2 min in those with inferior MI; the difference was not significant. Size of Infarction There were no significant differences in creatine kinase, lactate dehydrogenase, left ventricular ejection fraction and left ventricular … Continue reading

Effect of Infarct Site on Diastolic Time During Exercise: Statistical Analysis

Coronary Arteriography and Ventriculography Coronary arteriography was performed within 1 week prior to the exercise test. Coronary artery lesions with 70 percent or more reduction in diameter were considered to be obstructive. Each patient was classified as having one, two, or three-vessel disease, but patients with multivessel disease were not included in this study. Regional left ventricular wall motion abnormalities were assessed by biplane ventriculography. … Continue reading

Effect of Infarct Site on Diastolic Time During Exercise: Exercise Protocol

Supine bicycle ergometer exercise was performed when the patients were in the postabsorptive state. Two or 3 days before the study, supine bicycle exercise was performed to familiarize the patients with a bicycle ergometer (Monark 881E ergometer, Sweden). On the day of study, a Swan-Ganz catheter was inserted through the internal jugular vein and advanced to the pulmonary artery. An arterial catheter was inserted in … Continue reading

Effect of Infarct Site on Diastolic Time During Exercise: Methods

Diastolic time (DT), an important determinant of myocardial oxygen supply, has been shown to have a nonlinear relation to heart rate (HR) in various conditions. DT is especially important to the residual functioning myocardium of the noninfarcted segment after acute myocardial infarction (MI) because subendocardial blood flow decreases with increased intra-myocardial pressure. A higher mortality rate has been reported after anterior wall than after inferior … Continue reading